Levofloxacin Associated Fatal Oro-Facio-Brachial Dystonia in Cirrhosis

Fluroquinolones are rarely associated with severe dystonic syndromes. We present the case of a middle aged cirrhotic who presented with severe fatal oro-facio-brachial dystonia secondary to intravenous Levofloxacin use. Levofloxacin has been very rarely shown to be associated with such severe involuntary movement disorders. A commonly used antibiotic as part of anti-tubercular regimen, caution must be maintained for prevention of severe adverse reactions while using Levofloxacin.